This short blogpost illustrates optogenetics — a radical new technology for controlling brain activity with light that I recently rediscovered. Optogenetics is an emerging field of research that is combing ‘optics‘ with ‘genetics’ to modify the activities of brains.
Researchers genetically modify certain neurons to activate when they receive pulses of light. This is part of the medical field that is studying how to stimulate specific areas of the brain to relieve a host of chronic neurological aliments ranging from depression to Parkinson’s disease.
This post might be a bit ‘out-of-the-box’, and too research minded. But it think this interesting topic is worth mentioning. Impressive to see what the power of optics and light can do, especially related to the human body and brains. Finally, here’s a movie from MITTechTV explaining this new phenomenon in research:
[Pictures and animations in this post are courtesy of Sputnik Animation, Ed Boyden, and McGovern Institute for Brain Research.]
Light behaves both as a particle and as a wave. Since the days of Einstein, scientists have been trying to directly observe both of these aspects of light at the same time. Now, scientists at EPFL have succeeded in capturing the first-ever snapshot of this dual behavior.
Quantum mechanics tells us that light can behave simultaneously as a particle or a wave. However, there has never been an experiment able to capture both natures of light at the same time; the closest we have come is seeing either wave or particle, but always at different times. Taking a radically different experimental approach, EPFL scientists have now been able to take the first ever snapshot of light behaving both as a wave and as a particle. The breakthrough work is published in Nature Communications.
Credit: Fabrizio Carbone/EPFL
The first-ever snapshot of dual light behavior: Light behaving both as a particle and as a wave.
When UV light hits a metal surface, it causes an emission of electrons. Albert Einstein explained this “photoelectric” effect by proposing that light – thought to only be a wave – is also a stream of particles. Even though a variety of experiments have successfully observed both the particle- and wave-like behaviors of light, they have never been able to observe both at the same time.
A new Approach on a Classic Effect
A research team led by Fabrizio Carbone at EPFL has now carried out an experiment with a clever twist: using electrons to image light. The researchers have captured, for the first time ever, a single snapshot of light behaving simultaneously as both a wave and a stream of particles particle.
The experiment is set up like this: A pulse of laser light is fired at a tiny metallic nanowire. The laser adds energy to the charged particles in the nanowire, causing them to vibrate. Light travels along this tiny wire in two possible directions, like cars on a highway. When waves traveling in opposite directions meet each other they form a new wave that looks like it is standing in place. Here, this standing wave becomes the source of light for the experiment, radiating around the nanowire.
Shooting Electrons Stream on Nanowire
This is where the experiment’s trick comes in: The scientists shot a stream of electrons close to the nanowire, using them to image the standing wave of light. As the electrons interacted with the confined light on the nanowire, they either sped up or slowed down. Using the ultrafast microscope to image the position where this change in speed occurred, Carbone’s team could now visualize the standing wave, which acts as a fingerprint of the wave-nature of light.
A stream of electrons close to the nanowire, using them to image the standing wave of light.
The Wave-like Nature of Light
While this phenomenon shows the wave-like nature of light, it simultaneously demonstrates its particle aspect as well. As the electrons pass close to the standing wave of light, they “hit” the light’s particles, the photons. As mentioned above, this affects their speed, making them move faster or slower. This change in speed appears as an exchange of energy “packets” (quanta) between electrons and photons. The very occurrence of these energy packets shows that the light on the nanowire behaves as a particle.
A new Route towards Quantum Computing
“This experiment demonstrates that, for the first time ever, we can film quantum mechanics – and its paradoxical nature – directly,” says Fabrizio Carbone. In addition, the importance of this pioneering work can extend beyond fundamental science and to future technologies. As Carbone explains: “Being able to image and control quantum phenomena at the nanometer scale like this opens up a new route towards quantum computing.”
This work represents a collaboration between the Laboratory for Ultrafast Microscopy and Electron Scattering of EPFL, the Department of Physics of Trinity College (US) and the Physical and Life Sciences Directorate of the Lawrence Livermore National Laboratory. The imaging was carried out EPFL’s ultrafast energy-filtered transmission electron microscope – one of the two in the world.